ZEISS Axio Observer for Life Science Research​

Flexibility for Your Research

Axio Observer offers a dynamic interface tailored to the ever-evolving needs of life‑science research. It supports a wide range of imaging modalities—from brightfield transmission imaging to fast, friendly 3D sample sectioning—along with highly sensitive super‑resolution imaging techniques. You can select the ideal incubation system for your experiments while enjoying easy sample access and the ability to perform high‑precision operations. Numerous configurations allow you to broaden the capabilities of your Axio Observer and ensure flexible future upgrades or expansion.

Guidance for Your Workflows​

Reduce the time to image from minutes to just seconds. You will be amazed how easy imaging becomes when the AI Sample Finder automatically detects the sample carrier, adjusts the focus, and finds your sample region. Wizards guide you through the experimental setup for easy and intuitive selection of the imaging modalities for your applications. Acquired images can be easily combined with electron microscopy data and other modalities.​

Efficiency for Your Experiments

Expect a remarkable increase in efficiency with the Axio Observer automation functions. Fast switchable light sources and filters give you highest spectral flexibility and speed. Select the ideal camera to always get the image quality and speed your applications require. Whether keeping your sample in focus for long-term imaging or adapting your objective to your sample, it's all automatic with this highly organized system.

Automated Sample Identification for Efficient Imaging

Microscopes are becoming increasingly automated. However, sample placement, focus adjustment and identification of the relevant areas on the sample carrier still require manual steps. AI Sample Finder automates this sequence, eliminating time-consuming manual adjustments and reducing the time to image from minutes to just seconds.​

Optical Sectioning Using Structured Illumination​

With structured illumination, removal of out-of-focus light becomes simple and efficient. ZEISS Apotome 3 calculates your optical section from a number of images acquired with different grid positions. Get high-contrast images, even from thicker specimens, while your system remains just as easy to operate as always.

Cortical neurons. Widefield (left) and Apotome 3 (right). Courtesy of L. Behrendt, Leibniz-Institute on Aging – Fritz-Lipmann-Institut e.V. (FLI), Germany.

Minimize Your Risk. Improve Your Efficiency.

Immersion media between the sample and the objective is required for high-resolution imaging. Manual addition of immersion media risks loss of data points or even microscope damage from user error; it is also tedious and inefficient. The Autoimmersion Module for ZEISS Axio Observer 7 widefield and confocal systems is your automated, easy-to-use solution for maintaining immersion media for water immersion objectives.